Flexeril Cyclobenzaprine Hcl: Uses, Dosage, Side Effects, Interactions, Warning

Ell your doctor if your condition lasts after 2 to 3 weeks or if it gets worse. There are other drugs available to treat your condition. Talk with your doctor about other drug options that may work for you.

This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so. During pregnancy, this medication should be used only when clearly flexeril and diazepam needed. Animal studies don’t always predict the way humans would respond. Therefore, this drug should only be used in pregnancy if clearly needed. Many insurance companies require prior authorization for this drug.

FDA Drug Information

This means you may need to take it with other medications. Safety and effectiveness of FLEXERIL in pediatric patients below 15 years of age have not been established. Less frequent dosing should be considered for hepatically impaired or elderly patients (see PRECAUTIONS, Impaired Hepatic Function, and Use in the Elderly).

Another potential side effect of Flexeril abuse is cyclobenzaprine overdose, especially if taken in conjunction with other substances such as other CNS depressants like alcohol. Flexeril causes the body to become relaxed and abusing the substance in high doses can lead to cardiac arrest, low blood pressure, heart attack, and seizures. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction.

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Bedtime VLD CBP improved mood measured by the HAD scale and the HAD depression subscale. Subjects who received placebo showed no significant improvement in any of these measures. Together, these findings show that bedtime treatment with VLD CBP provided benefit to patients with FM by improving symptoms of pain, tenderness, fatigue, and depressed mood. Studies have compared cyclobenzaprine, methocarbamol, and other skeletal muscle relaxants and found that they are equally effective in treating acute musculoskeletal conditions. Cyclobenzaprine is one of the most studied skeletal muscle relaxants, with solid evidence and systematic reviews supporting its effectiveness.

As with all medications, the costs of cyclobenzaprine can vary. Cyclobenzaprine oral tablet may cause drowsiness and dizziness. This is more likely to happen in the few hours after you take it. Cyclobenzaprine may be used as part of combination therapy.

Bedtime musculoskeletal pain and fatigue

It is available in immediate-release tablets of 5 milligrams, 7.5 milligrams, and 10 milligrams and extended-release capsules of 15 milligrams and 30 milligrams and is usually given three times daily. The extended-release formulation should be administered at the same time each day. The capsule may be swallowed whole, but its contents also may be sprinkled onto a tablespoon of applesauce for immediate consumption without chewing the granules.

• It may decrease the signals from your brain that tell your muscles to spasm.
• Analysis of nocturnal sleep EEG CAP was determined by employing a computerized automatic detection analysis using the Embla PSG system27,31 that provides the frequency of total CAP and subtypes of CAPA1, CAPA2, and CAPA332,33.
• The usual dose is 5–10mg three times daily and treatment for more than 2–3 weeks is not recommended.
• Our compassionate, trained professionals are waiting to answer all your treatment questions.

If you take Flexeril as prescribed, there are minimal side effects. However, using Flexeril and alcohol can lead to Flexeril addiction. CYCLOBENZAPRINE (sye kloe BEN za preen) treats muscle spasms. It works by relaxing your muscles, which reduces muscle stiffness. It belongs to a group of medications called muscle relaxants. Laboratory data were summarized, and mean change was presented for each numeric variable.

Easily book a session with our online doctors to assist you with a wide range of non-life-threatening illnesses (including mental health conditions) from the comfort of your own home. If you have questions about side effects, call your doctor. If you have questions about side effects, call your child’s doctor. Call your child’s doctor for medical advice about side effects. Edmund has an extensive background in addiction research and medical writing, working collaboratively with doctors, substance use disorder specialists, and clinical experts across all content on Recovered.

Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. phenobarbital, phenytoin). Physostigmine is not recommended except to treat life-threatening symptoms that have been unresponsive to other therapies, and then only in close consultation with a poison control center. In the higher dose groups this microscopic change was seen after 26 weeks and even earlier in rats which died prior to 26 weeks; at lower doses, the change was not seen until after 26 weeks. Potential mechanisms for how bedtime CBP may improve FM symptoms are suggested by work on the sensation and regulation of pain in FM44. Many observations link these regions to central pain perception and the regulation of pain perception by descending inhibition45,46.